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OpenDue May 4, 2026·$6,000,000

Targeted Genome Editor Delivery (TARGETED) Challenge

Department of Health and Human Services - National Institutes of Health

Who can apply

The following Eligibility and Participation Rules will apply to this Challenge.

About this opportunity

Subject of the Challenge: Recent advancements in the genome editing technology field have enabled scientists to manipulate genomic sequences rapidly and efficiently. Despite revolutionary progress in this area, several challenges remain. Existing gene editing technologies like CRISPR-cas9, base editors and prime editors have great potential, but existing delivery technologies are not able to deliver gene editing technologies to many target tissues and cell types in sufficient quantities, which hinders clinical applications. While some cell types, like hepatocytes in the liver, have many delivery technologies capable of delivering genome editors, there are many other organs and cell types that are harder to reach. The Targeted Genome Editor Delivery (TARGETED) Challenge is a $6,000,000 chal...

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