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Specialized Programs of Research Excellence (SPOREs) in Human Cancers for Years 2027, 2028, and 2029 (P50 Clinical Trial Required)

National Institutes of Health

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Posted
Oct 23, 2025
Closes
Sep 25, 2029 (in 1076 days)

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Classification and identifiers

Solicitation number
PAR-28-022
Assistance listing (CFDA)
93.121

Amount

Amount not listed here. Check the official program.

Who can apply

Small businessState governmentsTribal organizationsNonprofitsHousing authoritiesPublic universities

Small businesses, State government agencies, Nonprofits, and Public colleges and universities can all apply here. Check the eligibility details below to see if your organization fits.

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

About this opportunity

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) invites applications for P50 Research Center Grants for Specialized Programs of Research Excellence (SPORE). This is a re-issuance of PAR-23-284 . The program will fund P50 SPORE grants to support state-of-the-art investigator-initiated translational research that will contribute to improved prevention, early detection, diagnosis, and treatment of an organ-specific cancer or a highly related group of cancers. For the purpose of this NOFO, a group of highly related cancers are those that are derived from the same organ system, such as gastrointestinal, neuroendocrine, head and neck, and other cancers. Other programmatically appropriate groups of cancers may include those centered around a common biologica...

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