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Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Optional)

National Institutes of Health

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Posted
Dec 17, 2025
Closes
Jan 7, 2028 (in 450 days)

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Classification and identifiers

Solicitation number
PAR-25-321
Assistance listing (CFDA)
93.394

Amount

Amount not listed here. Check the official program.

Who can apply

State governmentsTribal governmentsSchool districtsSpecial districtsFor-profitsLocal governments

State government agencies and Local government agencies can all apply here. Check the eligibility details below to see if your organization fits.

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

About this opportunity

Through this engineering-oriented Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to encourage submissions of exploratory/developmental Bioengineering Research Grant (EBRG) applications to demonstrate feasibility and potential utility of new capabilities or improvements in quality, speed, efficacy, operability, costs, and/or accessibility of solutions to problems in basic biomedical, pre-clinical, or clinical research, clinical care delivery, or accessibility.

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