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NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed)

National Institutes of Health

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Posted
Dec 17, 2025
Closes
Jan 7, 2028 (in 450 days)

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Classification and identifiers

Solicitation number
PA-25-304
Assistance listing (CFDA)
93.173

Amount

Amount not listed here. Check the official program.

Who can apply

State governmentsSchool districtsLocal governmentsNonprofitsPublic universitiesHousing authorities

State government agencies, Local government agencies, Nonprofits, including small and volunteer-run organizations, and Public colleges and universities can all apply here. Check the eligibility details below to see if your organization fits.

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

About this opportunity

The NIH Exploratory/Developmental Grant supports exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research.

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