HEAL Initiative: Whole Joint Health Program (R61/R33 Clinical Trial Required)
National Institutes of Health
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- Posted
- Feb 17, 2026
- Closes
- Oct 30, 2026 (in 32 days)
Similar opportunities open now
- HEAL Initiative: Translating Addiction Epidemiology, Prevention, Treatment, and Recovery Research into Practice (R61/R33 - Clinical Trial Optional)Same funderOpenNational Institutes of HealthCloses Feb 2029
- HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)Same funderOpenNational Institutes of HealthCloses Jan 2027Up to $350K
Classification and identifiers
- Solicitation number
- PAR-27-045
- Assistance listing (CFDA)
- 93.473
Amount
Amount not published by the funder
Who can apply
Public colleges and universities, Private colleges and universities, and Small businesses can all apply here. Check the eligibility details below to see if your organization fits.
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Foreign components, as defined in the NIH Grants Policy Statement and NOT-OD-25-155, are allowed.
About this opportunity
The National Center for Complementary and Integrative Health (NCCIH) plans to publish a Notice of Funding Opportunity (NOFO) that will support a phased mechanistic clinical research program focusing on understudied biological mechanisms that drive joint pain. The initiative responds to priorities identified in the 2023 HEAL Whole Joint Pain Workshop and supports the broader goals of the NIH Helping to End Addiction Long-term (HEAL) Initiative and the Make America Healthy Again vision by advancing safe, non-addictive, and prevention-oriented approaches to chronic pain. Joint pain affects nearly half of adults in the United States. Many current treatments provide incomplete or temporary relief, informed by clinical trials that focus on joint structures such as bone or cartilage in isolation,...