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Updated Application Policies: NIH Administrative Burden Reduction Effort Removal of Requirements for Letters of Intent and Unsolicited Applications Requesting $500,000 or More in Direct Costs

National Institutes of Health (NIH)

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Posted
Dec 7, 2025
Closes
No deadline published by the funder

At a glance

This funding opportunity is offered by National Institutes of Health (NIH). It is open to applicants nationwide.

Amount

Amount not published by the funder

Who can apply

NonprofitsHigher_EducationGovernment agencies

Nonprofits, including small and volunteer-run organizations and Government agencies can all apply here. Check the eligibility details below to see if your organization fits.

About this opportunity

Updated Application Policies: NIH Administrative Burden Reduction Effort – Removal of Requirements for Letters of Intent and Unsolicited Applications Requesting $500,000 or More in Direct Costs Notice Number: NOT-OD-26-019 Key Dates Release Date: December 03, 2025 Related Announcements July 24, 2025 – Notice to Applicants of Adjustments to Achieve Consistency in Peer Review Contacts and Processes. See Notice NOT-OD-25-135. Issued by NATIONAL INSTITUTES OF HEALTH (NIH) Purpose This Notice alerts the extramural research community of two important updates related to application submission policies.Letters of IntentEffective immediately NIH will no longer request or accept Letters of Intent (LOIs) as part of the application process. NIH has occasionally requested LOIs within Section IV of the ...

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