Updated Application Policies: NIH Administrative Burden Reduction Effort Removal of Requirements for Letters of Intent and Unsolicited Applications Requesting $500,000 or More in Direct Costs
National Institutes of Health (NIH)
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Updated Application Policies: NIH Administrative Burden Reduction Effort – Removal of Requirements for Letters of Intent and Unsolicited Applications Requesting $500,000 or More in Direct Costs Notice Number: NOT-OD-26-019 Key Dates Release Date: December 03, 2025 Related Announcements July 24, 2025 – Notice to Applicants of Adjustments to Achieve Consistency in Peer Review Contacts and Processes. See Notice NOT-OD-25-135. Issued by NATIONAL INSTITUTES OF HEALTH (NIH) Purpose This Notice alerts the extramural research community of two important updates related to application submission policies.Letters of IntentEffective immediately NIH will no longer request or accept Letters of Intent (LOIs) as part of the application process. NIH has occasionally requested LOIs within Section IV of the ...