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Optimizing Behavioral Sleep Interventions for Adolescents and Young Adults (R34 Clinical Trial Required)

National Institutes of Health

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Posted: Oct 23, 2025
Amount: $1,500,000
Closes: Oct 22, 2026 (in 84 days)

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Classification and identifiers

Solicitation number: RFA-MH-27-140
Assistance listing (CFDA): 93.242

Amount

$1,500,000

Who can apply

County governmentsNonprofitsPublic universitiesNonprofits (non-501c3)Local governmentsPrivate universities

Nonprofits, including small and volunteer-run organizations, Public colleges and universities, Local government agencies, and Private colleges and universities can all apply here. Check the eligibility details below to see if your organization fits.

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

About this opportunity

NIMH seeks applications for pilot research to adapt, optimize, and test behavioral interventions that address common sleep problems in adolescents and young adults with or at risk for a mental health disorder. This notice of funding opportunity (NOFO) supports pilot clinical trials designed to evaluate the feasibility, tolerability, acceptability, safety, and potential effectiveness of the approach in real world settings. Applications should aim to conduct a preliminary test of the intervention's impact on sleep and mental health outcomes, as well as an examination of the mechanisms that underlie the intervention's effectiveness, and to obtain preliminary data needed as a prerequisite for larger-scale effectiveness trials. In addition, interdisciplinary, collaborative teams of investigator...