Systematic Characterization of Genomic Variation to Assess Effects of Individual Variants on Genome Function and Phenotype (UM1 Clinical Trials Not Allowed)
National Institutes of Health
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- Posted
- Oct 23, 2025
- Amount
- $2,000,000
- Closes
- Dec 14, 2026 (in 65 days)
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Classification and identifiers
- Solicitation number
- RFA-HG-27-007
- Assistance listing (CFDA)
- 93.172
Amount
$2,000,000
Who can apply
Private colleges and universities, State government agencies, and Small businesses can all apply here. Check the eligibility details below to see if your organization fits.
About this opportunity
The National Human Genome Research Institute (NHGRI) intends to promote a new initiative by publishing a Notice of Funding Opportunity (NOFO) to solicit applications for research to characterize genomic variation to assess the impact of individual variants on genome function. This will be accomplished by systematically perturbing variants or elements using one or more high-throughput methods; collecting data on the effects of variants in DNA, RNA, or protein-coding elements on molecular, cellular, or organismal phenotypes; and developing robust, reproducible, and portable data processing pipelines. Centers funded through this initiative will become a part of the Impact of Genomic Variation on Function (IGVF) Consortium. As consortium members, centers will work together to ensure all consor...