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GREGoRi Technology Integration Center (U01, Clinical Trials Optional)

National Institutes of Health

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Posted: Oct 23, 2025
Amount: $2,250,000
Closes: Oct 30, 2026 (in 80 days)

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Classification and identifiers

Solicitation number: RFA-HG-27-012
Assistance listing (CFDA): 93.172

Amount

$2,250,000

Who can apply

Tribal governmentsPrivate universitiesFor-profitsNonprofits (non-501c3)State governmentsSpecial districts

Private colleges and universities and State government agencies can all apply here. Check the eligibility details below to see if your organization fits.

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

About this opportunity

The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. The purpose of this Notice of Funding Opportunity is to establish the GREGoRi Technology Integration Center, which will enable the development of standards and best practices for applying new and emerging molecular methods in rare disease diagnosis. A major deliverable of the Center will be a multidimensional dataset that can be used for the development and benchmarking of novel tools and strategies that facilitate rare disease diagnosis.