Discovery of in vivo Chemical Probes for the Nervous System (R01 Clinical Trial Not Allowed)
National Institutes of Health
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- Posted
- Oct 23, 2025
- Closes
- Mar 5, 2027 (in 219 days)
Classification and identifiers
- Solicitation number
- PAR-27-081
- Assistance listing (CFDA)
- 93.866
Amount
Amount not published by the funder
Who can apply
Nonprofits, including small and volunteer-run organizations and State government agencies can all apply here. Check the eligibility details below to see if your organization fits.
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
About this opportunity
The purpose of this Notice of Funding Opportunity (NOFO) is to support investigators who have the interest and capability to join efforts for the discovery of in vivo chemical probes for novel brain targets. It is expected that applicants will have, in hand, the starting compounds (validated hits) for chemical optimization and bioassays for testing new analog compounds.Through this NOFO, NIH wishes to stimulate research in:Discovery and development of novel, small molecules for their potential use in understanding biological processes relevant to the missions of National Institute of Mental Health (NIMH), National Institute on Drug Abuse (NIDA), National Eye Institute (NEI), and/or National Institute on Aging (NIA) andDiscovery and/or validation of novel, biological targets that will infor...