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Metastasis Research Network (U54 Clinical Trial Not Allowed)

National Institutes of Health

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Posted: Nov 20, 2025
Amount: $1,300,000
Closes: Sep 25, 2026 (in 57 days)

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Classification and identifiers

Solicitation number: RFA-CA-27-012
Assistance listing (CFDA): 93.396

Amount

$1,300,000

Who can apply

School districtsTribal governmentsHousing authoritiesCounty governmentsState governmentsNonprofits

State government agencies and Nonprofits, including small and volunteer-run organizations can all apply here. Check the eligibility details below to see if your organization fits.

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

About this opportunity

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits applications for research on developing a comprehensive and cohesive understanding of cancer metastasis. Towards this goal, the NCI will support U54 Specialized Centers that together will continue to serve as the hub of the Metastasis Research Network (MetNet). Each MetNet Center should propose an overarching scientific theme that will be pursued through two or three scientific inter- and multidisciplinary basic research projects. The projects should use integrative system level approaches to elucidate and integrate a mechanistic understanding of the non-linear, dynamic, and emergent processes in metastasis. Overarching themes should encompass the interplay between at least two central elements ...