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Notice of Changes to NIDCRs Clinical Terms of Award (CToA)

National Institutes of Health (NIH)

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Notice of Changes to NIDCR’s Clinical Terms of Award (CToA) Notice Number: NOT-DE-25-043 Key Dates Release Date: November 18, 2025 Related Announcements None Issued by National Institute of Dental and Craniofacial Research (NIDCR) Purpose The National Institute of Dental and Craniofacial Research (NIDCR) has revised its Clinical Terms of Award (CToA) to include information about NIDCR’s expectations on accrual and retention (A&R) monitoring of its clinical research portfolio. A&R monitoring expectations include NIDCR’s acceptance of a Study Accrual and Retention Plan, routine reporting of participant accrual, retention, and key study dates, and identification of accrual and/or retention challenges and strategies for improvement. Award recipients will complete these elements through the NID...

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