Critical Illness Immunological Reprogramming and Control Point Learning Engine (CIRCLE) Innovative Solutions Opening (ISO)
HEALTH AND HUMAN SERVICES, DEPARTMENT OF
Who can apply
No Set aside used. NONE
About this opportunity
The Advanced Research Projects Agency for Health (ARPA-H) is posting this Innovative Solutions Opening (ISO) solicitation in support of the Critical Illness Immunological Reprogramming and Control Point Learning Engine (CIRCLE) Program. ARPA-H anticipates that multiple Other Transaction (OT) Agreements will result from this announcement. CIRCLE seeks to create a critical illness Control Point Validation Engine that leads to improvements in intensive care unit (ICU) health outcomes, coupled to reduced stay time and associated costs, by assessing, predicting, and treating immuno-inflammatory dysregulation before it causes organ failure. Interested parties are invited to review the attached CIRCLE ISO ARPA-H-SOL-26-139 and its Attachments A � F. Proposer's Day: Wednesday, March 11, 2026 (ARPA...