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OpenDue June 24, 2026

Research Opportunity: DNA-Protein Epigenetic Chemistry Engineering (D-PECHE)

DEPT OF DEFENSE

About this opportunity

The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative proposals to demonstrate proof-of-concept for novel mechanisms for writing and erasing epigenetic base modifications in DNA. Mechanisms capable of modifying the epigenome offer new opportunities to control DNA-protein interactions and to study the functions and applications of rare or novel epigenetic modifications. This research opportunity will result in demonstrations of novel technologies to modify nucleic acids in vitro.

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