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OpenDue July 17, 2026

AI-Enabled Discovery of Broad-Spectrum Small-Molecule Inhibitors for Filoviruses

HEALTH AND HUMAN SERVICES, DEPARTMENT OF

Who can apply

No Set aside used. NONE

About this opportunity

AI-Enabled Discovery of Broad-Spectrum Small-Molecule Inhibitors for Filoviruses Purpose: The purpose of this Request for Information (RFI) is to conduct market research to identify s with capabilities in artificial intelligence (AI) for application in the discovery and advancement of broad-spectrum, small-molecule therapeutics targeting filoviruses (e.g., Ebola virus (EBOV), Sudan virus (SUDV), Marburg virus (MARV)). This RFI seeks information on technical capabilities, infrastructure, prior experience, and recommended approaches. Areas of interest include: AI-driven design, in vitro verification of hits, and early preclinical proof-of-concept evaluation. Information obtained through this RFI will inform acquisition planning and may shape the scope and structure of a future solicitation. ...

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