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STTR DTR27TZ02-NV001 (Defense Threat Reduction Agency): Biolab Mirror: Artificial Intelligence / Machine Learning (AI/ML) Digital Twin for Intent Characterization and Bio-Containment Integrity

U.S. Department of Defense — Defense Threat Reduction Agency

Posted
Nov 13, 2026
Closes
Jan 6, 2027 (in 54 days)

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Who can apply

small_business

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About this opportunity

Defense Threat Reduction Agency STTR topic — Accepting submissions 2026-12-02 to 2027-01-06. The proliferation of dual-use biological technologies and automated, high-containment laboratories globally presents a profound challenge to arms control verification and biosurveillance [3]. A state-sponsored facility operating under a declared, peaceful mandate (e.g., vaccine development, agricultural research) possesses all the necessary infrastructure, reagents, and personnel to rapidly pivot to unauthorized, non-compliant, or undeclared high-risk biological material production [2]. Current verification methods rely heavily on periodic physical inspections, voluntary declarations, and audits of digital LIMS. However, advanced adversaries can digitally spoof BMS, manipulate LIMS records, and co...

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