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Bioengineering Research Grants (BRG) (R01 Clinical Trial Optional)

National Institutes of Health

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Posted: Oct 23, 2025
Amount: $500,000
Closes: Jul 5, 2029 (in 1071 days)

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Classification and identifiers

Solicitation number: PAR-27-072
Assistance listing (CFDA): 93.399

Amount

$500,000

Who can apply

Small businessState governmentsNonprofitsNonprofits (non-501c3)School districtsCounty governments

Small businesses, State government agencies, and Nonprofits, including small and volunteer-run organizations can all apply here. Check the eligibility details below to see if your organization fits.

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

About this opportunity

This Notice of Funding Opportunity (NOFO) encourages collaborations between the life and physical sciences that: 1) apply a multidisciplinary bioengineering approach to the solution of a biomedical problem; and 2) integrate, optimize, validate, translate or otherwise accelerate the adoption of promising tools, methods, and techniques for a specific research or clinical problem in basic, translational, or clinical science and practice. An application may propose design-directed, developmental, discovery-driven, or hypothesis-driven research and is appropriate for small teams applying an integrative approach to increase our understanding of and solve problems in biological, clinical, or translational science. This NOFO will support clinical trials that test functionality or validate performa...