INCLUDE Project: Clinical Trials Phased Awards for Down syndrome Research (R61/R33 Clinical Trial Required)
National Institutes of Health
Free. Verify your email, then we send one reminder only.
- Posted
- Oct 23, 2025
- Amount
- Program total $3M
- Closes
- Jun 15, 2028 (in 642 days)
Similar opportunities open now
- INCLUDE Project: Exploratory/Developmental Research Awards for Down syndrome (R21 Clinical Trial Not Allowed)Same funderOpenNational Institutes of HealthCloses Jun 2028Up to $200K
- INCLUDE Project: Transformative Research Awards for Down syndrome (R01 Clinical Trial Not Allowed)Same funderOpenNational Institutes of HealthCloses Jun 2028Up to $500K
- Single-Site Investigator-Initiated Clinical Trials (R61/R33 Clinical Trial Required)Same funderOpenNational Institutes of HealthCloses Nov 2028
- NIH Small Business Innovation Research (SBIR) Phase IIB Strategic Breakthrough Award (Parent [R44] Clinical Trial Optional)Same funderOpenNational Institutes of HealthCloses Apr 2029
- Early-Stage Innovative Technology Development for Basic and Clinical Cancer Research (R61 Clinical Trial Not Allowed)Same funderOpenNational Institutes of HealthCloses in 59 daysUp to $150K
Classification and identifiers
- Solicitation number
- RFA-OD-27-005
- Assistance listing (CFDA)
- 93.395
Amount
Program total $3M
Who can apply
Nonprofits, including small and volunteer-run organizations and Small businesses can all apply here. Check the eligibility details below to see if your organization fits.
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
About this opportunity
The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. The purpose of this Notice of Funding Opportunity (NOFO) encourages Exploratory/Developmental Phased Innovation (R61/R33) grant applications to support development of clinical trials to treat critical and co-occurring health conditions in individuals with Down syndrome. The proposed research aims should be milestone-driven. The total project period for an application submitted in response to this NOFO may not exceed five years. This NOFO provides support for up to two years (R61 phase) for preliminary/developmental/planning studies, followed by possible transition to clinical trial support (R33) of...