Seed Instrumentation Support (SIS) Program (S10 Clinical Trial Not Allowed)
National Institutes of Health
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- Posted
- Nov 20, 2025
- Amount
- $50,000 - $400,000
- Closes
- Jul 1, 2028 (in 690 days)
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Classification and identifiers
- Solicitation number
- PAR-27-021
- Assistance listing (CFDA)
- 93.855
Amount
$50,000 - $400,000
Who can apply
Small businesses, Nonprofits, including small and volunteer-run organizations, and State government agencies can all apply here. Check the eligibility details below to see if your organization fits.
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/Foreign Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
About this opportunity
This Notice of Funding Opportunity (NOFO) aims to build new research capacity and develop a sustainable research program by supporting the purchase of a single commercially available biomedical research instrument currently unavailable in the institution. Instruments funded through this program must be shared among the users to create new research opportunities, enable reproducible data generation, encourage collaborative research and training, and strengthen long-term research capabilities. The minimum award is $50,000. While there is no limit on the total cost of the instrument, the maximum award is $400,000.
Related opportunities
- Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed)National Institutes of HealthCloses Jul 2028Up to $5M
- SBIR/STTR Commercialization Readiness Pilot (CRP) Program (Parent SB1 Clinical Trial Optional)National Institutes of HealthCloses Apr 2029
- NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)National Institutes of HealthCloses Apr 2027
- NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)National Institutes of HealthCloses Apr 2027
- Early-Stage Innovative Technology Development for Basic and Clinical Cancer Research (R61 Clinical Trial Not Allowed)National Institutes of HealthCloses Nov 2026Up to $150K
- NIH Small Business Innovation Research (SBIR) Phase IIB Strategic Breakthrough Award (Parent [R44] Clinical Trial Optional)National Institutes of HealthCloses Apr 2029