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NIH Director’s Pioneer Award (DP1 Clinical Trial Optional)

National Institutes of Health

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Posted: Dec 12, 2025
Amount: $700,000
Closes: Sep 9, 2026 (in 27 days)

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Classification and identifiers

Solicitation number: RFA-RM-27-001
Assistance listing (CFDA): 93.310

Amount

$700,000

Who can apply

State governmentsPublic universitiesCounty governmentsPrivate universitiesTribal organizationsNonprofits

State government agencies, Public colleges and universities, Private colleges and universities, and Nonprofits, including small and volunteer-run organizations can all apply here. Check the eligibility details below to see if your organization fits.

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

About this opportunity

The NIH Director"s Pioneer Award supports individual scientists of exceptional creativity who propose bold and highly innovative research projects with the potential to produce a major impact on broad, important areas relevant to the mission of NIH. To be considered pioneering, the proposed research must reflect substantially different scientific directions from those already being pursued in the investigator"s research program or elsewhere. Applications in all topics relevant to the broad mission of NIH are welcome. Research may involve basic, translational, or clinical research. The NIH Director"s Pioneer Award is a component of the High-Risk, High-Reward Research (HRHR) program of the NIH Common Fund.